Metabolic bone diseases: basic and clinical aspects

Male Equivalent Polycystic Ovarian Syndrome: Hormonal, Metabolic and Clinical Aspects

Recent studies identified the presence of a male polycystic ovarian syndrome (PCOS), which mainly affects men whose female relatives are afflicted with PCOS, caused by genes responsible for the susceptibility of this syndrome in women. Similar hormonal, metabolic, and clinical alterations occurring in PCOS women have also been reported in their male relatives, suggesting a association between t...

Endothelium and Cancer: Basic and Clinical Aspects

Thromboembolic complications as well as laboratory abnormalities in hemostatic parameters are frequently observed in cancer patients. Tissue factor (TF) has been documented to play a crucial role in the pathophysiology of thrombosis and, among other coagulation proteins, in tumor growth and metastatic spread. The principal inhibitor of TF-dependent pathway of blood coagulation is tissue factor ...

Metabolic bone diseases: an overview.

Basic and clinical aspects of olfaction.

Disturbances of olfaction are a common occurrence in many neurological and neurosurgical patients and their correct diagnosis might be helpful in management and enhancement of quality of life. However, olfaction is seldom checked in most neurosurgical units and the "smell bottles" are often either absent or out of date. This chapter reviews systematically recent advances in our understanding of...

Tuberculosis: Basic and Clinical Relevant Aspects

Tuberculosis remains a major public health problem around the world. This disease is caused by M. tuberculosis. The World Health Organization (WHO) estimated 10.4 million new tuberculosis cases worldwide in 2015 and 1.4 million of deaths in the same period. Besides, an estimated of 2 billion people worldwide have latent tuberculosis infection, from which 10% will develop tuberculosis disease. T...